Creatinine Clearance (Cockcroft-Gault)
The estimate most drug labels still specify for renal dose adjustment.
When to use it. Renal dose adjustment, where the licence was written against Cockcroft-Gault — including most direct oral anticoagulants.
Сведения о медицинской безопасности на этой странице показаны на английском. Их ещё не проверил врач, читающий на Русский, а полагаться на перевод, который никто не проверил, небезопасно.
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Limits of this score. Not interchangeable with eGFR: this returns mL/min for the actual person, not mL/min/1.73 m². Which body weight to use is a clinical decision — actual weight over-estimates clearance in obesity, so many protocols use ideal or adjusted body weight. Enter the weight your protocol specifies.
Sources
- Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976.
Where this is written from. This site is written from Indian clinical practice. Drug availability and brand names, vaccination schedules, national health programmes and some reference cut-offs differ between countries — a schedule or a threshold that is standard here may not be standard where you are. If you are reading outside India, check anything on this page against your own country’s guidance before you act on it.
Educational use only — not medical advice. Never a substitute for clinical judgement.